To date, there have been no quantitative in vivo assessments of contrast volumes and injection rates using modern high flow catheters during coronary angiography. Contrast volumes (n ؍ 554), injection durations (n ؍ 563), and injection rates (n ؍ 498) were collected during 88 cardiac catheterizations. With increasing cathetersize (6, 7, and 8 French), injection volume increased (P F 0.0001), duration decreased (P F 0.0001), and rate increased (P F 0.0001). Compared with injections into the right coronary artery, left coronary artery injections were larger (7.1 ؎ 0.1 cc vs. 4.8 ؎ 0.1 cc, p F 0.0001), longer (3.6 ؎ 0.05 sec vs 3.0 ؎ 0.07 sec, P F 0.0001) and faster (2.1 ؎ 0.04 cc/sec vs. 1.7 ؎ 0.06 cc/sec, P F 0.0001). Patients with a significant stenosis in the left main or proximal right coronary artery received less contrast (P F 0.0001) more slowly (P F 0.0001) over a similar duration of injection (P ؍ NS). When collaterals arose from the injected artery, angiographers injected more contrast (P F 0.001) over a longer period (P F 0.0001) more slowly (P F 0.0001). Catheter size and the injected vessel's location and anatomy significantly affect coronary catheterization injection technique. Cathet. Cardiovasc.
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