Application of nanofluids flooding in the oil and gas industry is recently emerging as enhanced oil recovery methods. Nanoparticles have the ability to alter the rock formation in order to recover oil trapped in the pores of the rock to improve oil recovery. In this study, core plug samples were formulated in the laboratory to investigate the effect of nanoparticles on oil recovery. The formulated core samples were saturated in low salinity brine. However, low salinity brine was used because it has the ability to alter rock wettability. After core flooding with brine for secondary recovery process, extracted oil from Irvingia gabonensis was introduced into the formation to investigate the effect of Irvingia gabonensis on oil recovery. The result of the study showed that magnesium oxide, silicon oxide, aluminum oxide and zinc oxide had oil recovery of 38.1%, 45.6%, 47.7% and 35.1%, respectively. However, when the nanofluids with Irvingia gabonensis were injected into the formation as a displacing agent, the oil recovery greatly improved to 50.3%, 52.0%, 53.2% and 52.4% for (MgO, SiO2, Al2O3 and ZnO). The result of the study showed that nanofluid flooding is a promising potential to improve oil recovery in the Niger Delta.