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Background Breast cancer is the fifth most common cause of death from cancer in women worldwide. In Brazil, mortality rates are increasing. Therefore, the aim of this study is to analyze breast cancer mortality between 2000 and 2018 in Mato Grosso, a Brazilian state in Legal Amazon. Methods Ecological study analyzing temporal trends. Data were extracted from the Mortality Information System. The selected variables were: sex (female), cause of death (C-50, in the 10th revision of the International Classification of Diseases - ICD 10), age (less than 50 years-old, equal or older than 50 years-old) and year of death (2000-2018). Resident population data were obtained from the Ministry of Health's database (DATASUS) for calculation of breast cancer annual mortality rates. Temporal trends were estimated using linear regression. All analyses were done in the STATA 14.0. Results Between 2000 and 2018, 2,276 deaths from breast cancer were registered in women. Of these, 756 (33.2%) in the youngest age group and 1,520 (66.8%) in the oldest age group. A statistically significant increase in breast cancer mortality was found for both age groups (p < 0.001). In the annual mortality rates analysis, women in the youngest age group had the lowest rate in 2003 (1.98 deaths/100,000 women) and the highest rate in 2018 (7.88 deaths/100,000 women). The oldest age group had the lowest mortality rate in 2000 (21.48 death/100,000 women) and the highest rate in 2017 (47.09 deaths/100,000). The mean mortality rate was 5.69 for the youngest age group and 33.19 for the oldest age group. The annual percentage of change was 33.31 for the youngest group and 62.49 for the oldest group. Conclusions There is a statistically significant increase in female breast cancer mortality rate in Mato Grosso, one of the Brazilian states in Legal Amazon. It is imperative to invest in breast cancer screening to enable the reduction of the mortality rate of the disease. Key messages Our study presents information of breast cancer in a state from Legal Amazon that has increased death rates by the years 2000 to 2018. Besides breast cancer is relevant in Brazil, this is the first analysis from this specific data, potential to support improvement in disease control.

Background Colorectal cancer has been one of the cancers that most contributed to mortality, in both sexes in the world. In Brazil, cancer is among the top five causes of death and colorectal cancer is ranked on the fifth position. Of the Federative Units belonging to the Legal Amazon, Mato Grosso stands out for the higher adjusted incidence of colorectal cancer for both sexes. Thus, the objective is to characterize deaths from colorectal cancer, according to sociodemographic variables in Mato Grosso from 2000 to 2016. Methods A descriptive study was carried out, using data from the Mortality Information System, made available by the Department of Health of the Mato Grosso State. Deaths of all ages were selected, whose basic cause was identified by the codes from the International Classification of Diseases: (C.18) colon cancer, (C.19) rectosigmoid junction cancer, (C.20) rectal cancer or (C.21) anus cancer. Results Between 2000 and 2016, 31,607 deaths from cancer were registered. Of these, 1,750 (5.6%) were due to colorectal cancer. An increased number of deaths was observed at the end of the period, with a variation from 46 deaths in 2000 from 173 in 2016. Highest frequency was verified in men (51.3%), people aged 60 years or older (59.7%), black (54.6%), married (52.3%) and those with primary education (55.2%). According to Brazilian occupation classification options or those answers filled out on the death certificate, highest frequency were for “Retired” (26.2%), “Housewife” (23.1%), Agricultural/Forestry and Fisheries” (11.3%) and “Production of Industrial Goods and Services” (10.3%). Conclusions This study evidenced the increased number of deaths due to colorectal cancer in Mato Grosso State, and identified priority groups for interventions through public health policies which should include screening and early diagnosis to cope with the disease. Key messages Evidenced the increased number of deaths due to colorectal cancer in Mato Grosso State. Identified priority groups for interventions through public health policies.