The incidence of clinically apparent neonatal thrombosis is about 0.1 to 0.2% in the neonatal intensive care unit (NICU). The optimal treatment modalities for neonates with thromboses are not known. We report on our experience with recombinant tissue type plasminogen activator (rt-PA) in a premature infant with an intracardiac thrombus.

Highlights a) Male sex and the development of acute distress respiratory syndrome are two independent risk factors for ICU admission. b) Admission in the Intensive Care Unit occurs in 10% of all those hospitalised for influenza. c) Influenza confirmed patients show higher detection rates of influenza A virus.