Methods. We took a sample of 100 patients over 65 years old from the Polyclinic of the European University of Madrid. The oral symptoms were reported, in most of cases consisting of xerostomia associated to drugs, denture ulcers, gingival bleeding associated with anticoagulant therapy and tooth mobility among others. We also studied risk factors, systemic diseases and prescribed medication as well as oral hygiene and used or worn prosthetic elements. As far as oral pathology, we performed an extra and intraoral exploration. We searched for ulcerative lesions, lingual, viral, bacterial, fungal and autoimmune pathology among others, associated to poor hygiene, caries, gingival recession and periodontal disease. Results. Traumatic ulcer associated to prosthesis in poor condition was the most common oral lesions in the study group. The most common symptom was xerostomia associated with the consumption of drugs. Conclusion. Increased life expectancy and declining birth rates are responsible for the aging of population in Spain and in other developed countries. The dentist and other health professionals must recognize this social change and focus actions to the prevention and detection of oral lesions and symptoms caused by systemic disorders.