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A determination was made of total urinary adenosine 3'-5'cyclic monophosphate (UcAMP), nephrogenous cyclic AMP (NcAMP) excretion and also of the renal tubular maximum reabsorptive capacity for phosphate T,P04/GFR (all expressed as a function of the glomerular filtrate) in fourteen patients with primary hypercalcaemic hyperparathyroidism and twelve control normal subjects. The hyperparathyroid patients gave a mean excretion of UcAMP (7.45f0.68 nmo1/100ml GF; mean+SEM), NcAMP(6~19+0~64nmo1/100ml GF) which were significantly greater (P <0.001) than those of normal controls,

Summary Normal values for serum cystine aminopeptidase (CAP) during pregnancy are established and compared with results from abnormal pregnancies. Steadily rising CAP values suggest adequate lacental function. A correlation exists between the final CAP value and birthweight in normal pregnancies. The implications of various trends in CAP results in abnormal pregnancies are considered.

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