According to our analysis, contemporary Global Education Politics (GEP) in Medicine is still dominated by a technocratic cognitive framework and content. For this reason we view it crucial to develop a novel educational framework for graduation in medicine with the Person-Centered Care concept implemented within it, as formulated by Juan E Mezzich and informed by the comprehensive assessment and values-based medical practice, developed by Bill (KWM) Fulford. Some of the outstanding training programs in medicine, dentistry and public health are already designed according to this novel approach. Key elements in the curriculum include:Society's Health and Ethics (Ethics and Public Health, pointers of values-based practice, values, evidence and ethics); Health research with a major focus on epistemology and methodology; Personal Life Psychology (life cycles, relationships, cultural diversity, lifestyle planning, stress management); Adverse life events (breaking of bad news, disability, grief and bereavement, euthanasia, suicide); The doctor-patient relationship (patient-centered consultation, problem solving and critical thinking, dealing with uncertainty and professional mistakes).Global medical education may be characterized by progress from facts-based (evidence) to integrative values-and-factsbased clinical education and management. If this is considered with respect to the Bulgarian medical model, which was designed according to German and Russian philosophies in the previous century, then there is a challenging, but nevertheless advantageous opportunity, for a reassessment of the model. In the context of the international movement for person-centered medicine, Bulgarian public health institutions are facing the demand for a proactive adjustment of the medical curriculum with the requirements of the global strategy for an introduction of this model in medical education and postgraduate training.