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Antiproliferative Hybrid Analogues of the Hormone 1α,25-Dihydroxyvitamin D3: Design, Synthesis, and Preliminary Biological Evaluation.-Seventeen analogues of the title compound are prepared and tested for in vitro antiproliferative activity. (XIVa) is found to parallel the high activity of natural dihydroxyvitamin D3 even at low nanomolar levels. -(POSNER, G. H.; LEE, J. K.; WHITE, M. C.; HUTCHINGS, R. H.; DAI, H.; KACHINSKI, J. L.; DOLAN, P.; KENSLER, T. W.; J.