Small- and medium-vessel vasculitis is a common manifestation in systemic lupus erythematosus (SLE) and may occur in any organ. However, acute acalculous cholecystitis is a rare abdominal manifestation in SLE, especially in children. We report a case of a 12-year-old patient who initially presented with AAC and seizure. Follow-up investigation diagnosed SLE, and brain magnetic resonance imaging had hyperintense white matter lesions in cortico-subcortical regions. The patient was successfully treated with pulse methylprednisolone and cyclophosphamide without surgical intervention.

Purpose of investigation:To assess the changes secondary to chronic inflammation in women with and without pelvic endometriosis by the determination of serum thiols and carbonyls. Materials and Methods: Sixty-seven women with endometriosis consecutively submitted to laparoscopy and 41 women without endometriosis consecutively submitted to tubal ligation (control group) were selected. Serum levels of total thiols and carbonyls were determined in both groups. Results: Patients with endometriosis had significantly lower thiol levels than controls (342.37 ± 142.09 µM vs 559.60 ± 294.05 µM) (p < 0.001), as well as significantly lower carbonyl levels (8.97 ± 3.76 µM vs 16.40 ± 9.26 µM) (p < 0.001). Other clinical characteristics were not associated with changes in marker levels. The cutoff point established by the ROC curve was 396.44 µM for the thiols, with 73.1% sensitivity and 80.5% specificity, and 14.9 µM for the carbonyls, with 94% sensitivity and 51.2% specificity. Conclusions: The serum thiol levels revealed an increase in oxidative stress related to the development of pelvic endometriosis.