No abstract

In a normative sample of 205 children ages 8-12, tracked into adulthood, we examined the predictive links between four childhood personality traits--Mastery Motivation, Academic Conscientiousness, Surgency, and Agreeableness--and adult personality and adaptation 20 years later. Personality demonstrated modest to moderate continuity over those two decades and showed significant predictive validity for success in adult life, including academic attainment, work competence, rule-abiding versus antisocial conduct, and romantic and friend relationships. Results indicated that personality shows coherent patterns over time in terms of both stability and linkages to adaptive behavior. Explicating the processes underlying such patterns is the next frontier for a truly developmental science of personality.

Objective The incidence of anal cancer is higher in women than men in the general population and has been increasing for several decades. Similar to cervical cancer, most anal cancers are associated with human papillomavirus (HPV) and it is believed that anal cancers are preceded by anal high-grade squamous intraepithelial lesions (HSIL). Our goal was to summarize the literature on anal cancer, HSIL and HPV infection in women, and provide screening recommendations in women. Methods A group of experts convened by the ASCCP and the International Anal Neoplasia Society reviewed the literature on anal HPV infection, anal SIL and anal cancer in women. Results Anal HPV infection is common in women but is relatively transient in most. The risk of anal HSIL and cancer varies considerably by risk group, with HIV-infected women and those with a history of lower genital tract neoplasia (LGTN) at highest risk compared with the general population. Conclusions While there are no data yet to demonstrate that identification and treatment of anal HSIL leads to reduced risk of anal cancer, women in groups at the highest risk should be queried for anal cancer symptoms and have digital anorectal examinations to detect anal cancers. HIV-infected women and women with LGTN, may be considered for screening with anal cytology with triage to treatment if HSIL is diagnosed. Healthy women with no known risk factors or anal cancer symptoms do not need to be routinely screened for anal cancer or anal HSIL.

No abstract