Substances have been detected in extracts of British marine algae which interfere with the coagulation of human blood.The effects of these substances were found to be significantly different from those of heparin.Anti-coagulant activity was present in extracts prepared from species of Chlorophyta, Rhodophyta and Phaeophyta. This is the first report of such action in any species of Chlorophyta.

A case of agranulocytosis following clomipramine treatment is described. The period of agranulocytosis lasted for 19 days and was complicated by systemic Candida infection which was successfully treated with flucytosine.

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pital) services, but I beg leave to doubt if the ordinary G.P. should be expected to take on such an additional work load as proper family planning involves without being recompensed financially sufficiently to enable him to reduce the number of patients requiring his ordinary medical attention. I do not for a moment agree, in the present pressure existing in general practice, that he can, or should, simply try to add it onperhaps the last straw upon the camel's back?-I am, etc.,

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