O bjective: To study the role of biomarkers like microalbuminuria in acute ischemic stroke. Material and Methods: A total of 70 cases admitted in wards an d ICU under Department of Medicine, NIMS Medical College & Hospital Jaipur and 70 controls that were the normal age/sex matched during study period of 15 months i.e. July 2014 to September 2015 were taken into study based on inclusion and exclusion criteria. Urine for microalbumin is tested at the time of admission. Stroke severity and prognosis is assessed by NIHSS score on day 0, 3, 7 & 14. Tests of statistical significance were done using Chi-square Test, unpaired’t’ test and fisher test. Results: Out of 70 age and sex matched cases and controls, Microalbumiuria is seen in 51.43% of cases an d 2.86% of controls, which is statistically significant (P <0.001). Mean urine albumin creatinine ratio (UACR) is 65.10 + 79.12 in cases where as it is 7.53 + 8.04 in controls which is also statiscally significant (p<0.001). Hence MA is considered as a risk factor in acute ischemic stroke. Among 70 acute ischemic stroke cases studied, MA was seen in 36 in whom 11 patients fell in severe NIHSS score and 16 very severe which is statistically significant (Chi-square = 27.605 with 3 degrees of freedom; P <0.001) * Mean NIHSS sco re for the patients with MA at the time of admission and discharge was 22.05 and 16.16 compared to 8.36 and 3.61 at the time of admission and discharge in patients without MA , most of our comatose patients had microalbuminuria thus predicting seriousness of stroke in patients with microalbumin uria. Conclusion: We found that MA is an independent risk factor and potential prognostic marker in acute ischemic stroke.

Aims & Objectives: To study the profile of Autosomal Dominant Polycystic Kidney Disease (ADPKD) in low lying areas of NorthIndia. This is a 2 year observation study of patients attending Nephrology department in National Institute of Medical Sciences, Shobha Nagar, Jaipur, Rajasthan, India. Material & Methods: This is a 2 year prospective study done in National Institute of Medical Sciences- a tertiary hospital in rural area close to Jaipur. All ADPKD patients attending Nephrology department were studied to know their complete profile. Results: A total of 54 ADPKD patients attended Nephrology department between Jan 2014-Jan 2016, Out of which 34 patients presented with pain abdomen, 22 patients with hypertension, 8 patients with chronic renal failure kept on medical management, 8 with Chronic Kidney Disease CKD-ESRD (End Stage Renal Disease) on maintenance hemodialysis(MHD). Out of these 8 CKD-ESRD, there were 4 incidents of AV fistula thrombosis and 1 died recently whereas 20 patients remained completely asymptomatic. Conclusion: Timely diagnosis, proper understanding of disease by patients will provide good quality of life in these patients. Low salt diet, good control of hypertension (<130/80 mm of hg) delays progression to ESRD in these patients.