animals to maintain a normal acid-base equilibrium of the blood and to eliminate phenolsulphanephthalein.Structural modification associated with the ageing process which may or may not be designated disease, has resulted in the stabilization of a fundamental equilibrium of the animal organism as the animal relates itself to its normal environment and to an abnormal environment brought about by the introduction of a chemical body foreign to its tissues.Summary. Twenty-three senile dogs showing varying degrees of glomerular in jury and at the same time a fairly diffuse change in the type of epithelium in the proximal segment of the renal nephron from a normal order of cuboidal cell to one of a flattened, less spe-cialized type of cell when subjected to the anesthetic action of chloroform for 45 minutes fail to show, as the result of the use of this body, a reduction in the elimination of phenolsulphanephthalein, or a reduction in the reserve alkali of the blood from that value which these animals have established as their pathological normal. In a group of 29 control senile animals, with a normal urine, both chemically and microscopically, with the same order of change in the glomeruli but with, in general, a normal order of cytological structure in the proximal segment of the renal nephron when anesthetized for 45 minutes with chloroform show a marked decrease in the elimination of phenolsulphanephthalein and a reduction in the reserve alkali of the blood.

The present report is concerned with the reflex sensitivity to visual stimulation of the blind half of the retinal field in a case of hemianopsia after surgical resection of the left occipital lobe.t The

No abstract

Case 2A 32 year old Asian man presented with a three week history of poor appetite, weight loss, diarrhoea, sweating, tremor of the hands, and paraesthesia in the extremities and face. Symptoms developed four weeks after treatment for eczema had been started by the same hakim who had treated the first patient.On examination the patient was anxious, flushed, tachycardic, and hypertensive, with a fine tremor of the outstretched hands. Neurological examination showed reduced pinprick sensation in both feet. Standard laboratory investigations, including thyroid function tests, all gave normal findings. Mercury poisoning was confirmed by a urinary mercury concentration of 105 ,ug/l (normal < 10 ,ug/l, toxic concentration > 100 ,ug/l) 12 weeks after the last exposure to the ethnic remedies. Analysis of the handmade redbrown pills which the hakim had prescribed at a dose of six daily showed each to contain 30-42 mg of inorganic mercuric sulphide (table).

No abstract