The development of accurate techniques for spinal stereotaxic surgery facilitates the difficult management of post-herpetic facial pain by making possible destruction of both the spinal trigeminal nucleus and descending tract; it also elminates excitation from the nuclear overlap between cervical and facial segments and intranuclear pathways. The technique is described and three cases reported. Stereotaxic trigeminal tractotomy relieves both the hyperpathia and deep background pain of herpes.KEy WoRDs herpes zoster facial neuralgia trigeminal nucleus tractotomy stereotaxis LTHOUGH post-herpetic neuralgia is not an invariable concomitant of shingles, its incidence increases with age and its management is often difficult. It occurs in 10% to 15% of all post-herpetic neuralgias, 19,~5 second only in frequency to truncal pain. Although pain may be experienced in any portion of the head or face ~ it almost invariably involves the area served by the ophthalmic division of the fifth nerve. ~,28 Tatlow,~8 however, reported only seven of 47 patients with ophthalmic herpes who developed pain or abnormal sensations, and only one of these required surgical treatment.Among the diverse medical treatments are the use of vitamin B12, Diphenylhydantoin, Tegretol, and analgesics; electric massage or percussion ~1 has produced equivocal results. Surgical therapy has been equally diverse, including such peripheral measures as undermining the skin, excision of the scarred area, and avulsion of sensory nervesY 9 White and Sweet ~~ have concluded that conservative therapy should be attempted first with electrical massage or subcutaneous infiltration of the painful skin with steroids; if this fails they suggest the elevation of a large flap of the painful skin or avulsion of its sensory nerve supply provided that preliminary regional anesthesia stops the pain. Sympatheetomy has been helpful in some cases? ,11The results of thalamotomy have been uncertain? 6 Sensory cortical excision has not been very successful, za,~G and is attended by a high risk of epilepsy. The poor results of many of these treatments is shown by Sugar and Bucy's ~6 review; their final conclusion was that only bifrontal lobotomy was successful in relieving the pain of post-herpetic ncuralgia.Almost without exception the results of direct attack on the trigeminal nerve, its branches, or central connections have failed. :~,~,,~,~5,~ White and Sweet 3~ suggest that bulbar tractotomy or trigeminal rhizotomy should be considered for cases where peripheral neurectomy gives some months of adequate relief, and for the most intractable group advise stereotaxic thalamotomy or upper mesencephalotomy.Our own experience 9,~~ has been that pc-412 1. Neurosurg. / Volume 37 / October, 1972
SUMMARY Posterior hypothalamotomy is a relatively simple stereotactic procedure. The radiological determination of the target and its physiological corroboration by electrical stimulation are accurate. The lesions have always been made in the site of maximum sympathetic response. In this respect, the cardiovascular changes (hypertension and tachycardia), which are always elicited from a more restricted area, are of particular importance. Depth recordings, however, have been less useful. Undesirable side-effects, if present, were mild and transitory. There was no postoperative intelligence deficit, at least with the standard tests.Soon after the suggestion that particular areas of the brain were involved in emotional behaviour, Bard (1928) showed that removal of all nervous tissue rostral, dorsal, and lateral to the hypothalamus did not abolish sham rage phenomena in decorticate preparations. However, sections caudal to the hypothalamus eliminated this response (Bard and Rioch, 1937;Bard, 1939).Hess, in 1927, using chronically implanted electrodes in cats, elicited a wide variety of 'affective-defensive' reactions from hypothalamic stimulation, which were of somatic, autonomic, and behavioural type. These purposeful and well coordinated responses could be obtained from a relatively extensive area, although with lower threshold from the perifornical region (Hess, 1954(Hess, , 1969.Later papers suggest that a wide variety of behavioural patterns depend upon relatively specific hypothalamic structures (Ranson and
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