ObjectiveMany troops deployed in Iraq and Afghanistan have sustained blast-related, closed-head injuries from being within non-lethal distance of detonated explosive devices. Little is known, however, about the mechanisms associated with blast exposure that give rise to traumatic brain injury (TBI). This study attempts to identify the precise conditions of focused stress wave energy within the brain, resulting from blast exposure, which will correlate with a threshold for persistent brain injury.MethodsThis study developed and validated a set of modelling tools to simulate blast loading to the human head. Using these tools, the blast-induced, early-time intracranial wave motions that lead to focal brain damage were simulated.ResultsThe simulations predict the deposition of three distinct wave energy components, two of which can be related to injury-inducing mechanisms, namely cavitation and shear. Furthermore, the results suggest that the spatial distributions of these damaging energy components are independent of blast direction.ConclusionsThe predictions reported herein will simplify efforts to correlate simulation predictions with clinical measures of TBI and aid in the development of protective headwear.

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The containment building surrounding a nuclear reactor offers the last barrier to the release of radioactive materials from a severe accident into the environment. The loading environment of the containment under severe accident conditions may include much greater than design pressures and temperatures. Investigations into the performance of containments subject to ultimate or failure pressure and temperature conditions have been performed over the last several years through a program administered by the Nuclear Regulatory Commission (NRC). These NRC sponsored investigations are subsequently discussed. Reviewed are the results of large scale experiments on reinforced concrete, prestressed concrete, and steel containment models pressurized to failure. In conjunction with these major tests, the results of separate effect testing on many of the critical containment components; that is, aged and unaged seals, a personnel air lock and electrical penetration assemblies subjected to elevated temperature and pressure have been performed. An objective of the NRC program is to gain an understanding of the behavior of typical existing and planned containment designs subject to postulated severe accident conditions. This understanding has led to the development of experimentally verified analytical tools that can be applied to accurately predict their ultimate capacities useful in developing severe accident mitigation schemes. Finally, speculation on the response of containments subjected to severe accident conditions is presented.