The Henderson Hospital is a 68 bed unit for the in-patient treatment of young people of both sexes who are described as psychopaths, sociopaths, personality disorders or character disorders. Treatment is by means of a Therapeutic Community, and prospective patients are referred by external psychiatrists with no working commitment in the hospital, by prison medical officers and sometimes by Probation Officers and other social workers with the medical backing of a general practitioner. All prospective patients are seen at a group interview and on the basis of this will be selected for admission or not.

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Factors from the social history of male psychopaths were examined in relation to their success or failure as measured by re-convictions of psychiatric hospital re-admissions 2-3 years after treatment at Henderson Hospital. From these data a weighted prediction formula was calculated and was tested out on a further cohort of patients. As a prediction instrument it was found to be reliable to a degree of significance just above the 1 per cent level. Other aspects of the subsequent career of treated patients are noted, in particular a tendency to early but often short-lived relapse and then longer standing success.

Trifluoperazine (Stelazine) is a phenothiazine derivative and is 2-trifluoromethyl-10-(3′ 1″-methyl piperazinyl-4″-propyl) phenothiazine dihydrochloride. It is related to prochlorperazine, and in fact differs only in having a trifluoromethyl group in place of the latter's chlorine atom in position 2 of the nucleus. However, in laboratory studies, tests based on the inhibition of conditioned responses have indicated that this compound was 5 times as effective as prochlorperazine and 10 times as potent as chlorpromazine on a weight for weight basis.

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