Needle visualization in the ultrasound image is essential to successfully perform the ultrasound-guided core needle biopsy. Automatic needle detection can significantly reduce the procedure time, false-negative rate, and highly improve the diagnosis. In this paper, we present a CNN-based, fully automatic method for detection of core needle in 2D ultrasound images. Adaptive moment estimation optimizer is proposed as CNN architecture. Radon transform is applied to locate the needle. The network’s model was trained and tested on the total of 619 2D images from 91 cases of breast cancer. The model has achieved an average weighted intersection over union (the weighted Jaccard Index) of 0.986, F1 Score of 0.768, and angle RMSE of 3.73°. The obtained results exceed the other solutions by at least 0.27 and 7° in case of F1 score and angle RMSE, respectively. Finally, the needle is detected in a single frame averagely in 21.6 ms on a modern PC.

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