The goal of this work was to develop lateral flow immunoassays (LFAs) to biomarkers related to nicotine-containing products such as combusted tobacco, oral tobacco, and e-cigarettes. LFAs were screened to determine how well they discriminate users of nicotine-containing products from non-users. Additional analyses assessed if any developed LFAs show signs of distinction between the various use-groups (combusted tobacco, oral tobacco, and e-cigarettes). The following describes the development of cotinine, anabasine, and nicotelline LFAs as well as the test and analyses from 212 individual urine specimens.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.