The AMIA biomedical informatics (BMI) core competencies have been designed to support and guide graduate education in BMI, the core scientific discipline underlying the breadth of the field's research, practice, and education. The core definition of BMI adopted by AMIA specifies that BMI is 'the interdisciplinary field that studies and pursues the effective uses of biomedical data, information, and knowledge for scientific inquiry, problem solving and decision making, motivated by efforts to improve human health.' Application areas range from bioinformatics to clinical and public health informatics and span the spectrum from the molecular to population levels of health and biomedicine. The shared core informatics competencies of BMI draw on the practical experience of many specific informatics sub-disciplines. The AMIA BMI analysis highlights the central shared set of competencies that should guide curriculum design and that graduate students should be expected to master.

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n recent years there has been increasing interest in describing complicated information processing systems in terms of the knowledge they have, rather than by the details of their implementation. This requires a means of modeling the knowledge in a system. Several different approaches to knowledge modeling have been developed by researchers working in Artificial Intelligence (AI). Most of these approaches share the view that knowledge must be modeled with respect to a goal or task. In this article, we outline our modeling approach in terms of the notion of a task-structure, which recursively links a task to alternative methods and to their subtasks. Our emphasis is on the notion of modeling domain knowledge using tasks and methods as mediating concepts. We begin by tracing the development of a number of different knowledge-modeling approaches. These approaches share many features, but their differences make it difficult to compare systems that have been modeled using different approaches. We present these approaches and describe their similarities and differences. We then give a detailed description, based on the task structure, of our knowledge-modeling approach and illustrate it with task structures for diagnosis and design. Finally, we show how the task structure can be used to compare and unify the other approaches.

Many healthcare technology projects fail due to the lack of consideration of human issues, such as workflow, organizational change, and usability, during the design and implementation stages of a project's development process. Even when human issues are considered, the consideration is typically on designing better user interfaces. We argue that human-centered computing goes beyond a better user interface: it should include considerations of users, functions and tasks that are fundamental to human-centered computing. From this perspective, we integrated a previously developed human-centered methodology with a Project Design Lifecycle, and we applied this integration in the design of a complex distributed knowledge management system for the Biomedical Engineer (BME) domain in the Mission Control Center at NASA Johnson Space Center. We analyzed this complex system, identified its problems, generated systems requirements, and provided specifications of a replacement prototype for effective organizational memory and knowledge management. We demonstrated the value provided by our human-centered approach and described the unique properties, structures, and processes discovered using this methodology and how they contributed in the design of the prototype.