Importance: Targeted phototherapy for treatment of localized psoriasis has advantages over non-targeted phototherapy. It delivers high ultraviolet doses to only the diseased skin, sparing irradiation to normal skin. Objective: This study aims to review the devices that are available for targeted treatment of psoriasis. Evidence Review: A PubMed literature review was conducted to identify devices for localized psoriasis phototherapy. Device manufacturer websites were searched for specific information. Findings: Eighty-four papers were identified that met the inclusion criteria. We identified and described seven laser/light therapies and 22 devices for localized psoriasis treatment. Limitations: There is potential bias for each device since the products' information was provided by their manufacturer. Some devices were excluded due to lack of relevant information. Conclusions and Relevance: Excimer laser and narrow band ultraviolet B devices are valuable treatment modalities for localized psoriasis. Handheld, narrow band ultraviolet B devices are efficacious and available for home treatment.
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