The aim of this study was to evaluate intersectoral partnerships for mental health in the Brazilian Family Health Strategy. This was an evaluative, qualitative study guided by the Fourth Generation Evaluation framework, developed in a Family Health Strategy unit in a municipality of the state of Rio Grande do Sul. A total of 39 subjects (10 patients, 10 family members and 19 employees) were interviewed. As observed, intersectoral partnerships for mental healthcare are important, as they allow for greater freedom of patients with psychological distress. Among these, the partnership with the resident association and between the Family Health Strategy and the Federal University of Rio Grande do Sul stand out. Despite the difficulties, the consolidation of inclusive projects through an intersectoral approach is emerging as a new way to construct a healthcare agenda that is linked to the needs of the territory, and driven by the premises of the Brazilian Unified Health System.