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[Purpose] The aim of this study was to investigate the impact of different marathon running distances (10 km, 21 km, and 42.195 km) on muscle and lymphocyte DNA damage in amateur marathon runners. [Subjects and Methods] Thirty male amateur runners were randomly assigned to 10 km, 21 km, and 42 km groups, with 10 subjects in each group. Blood samples were collected before and after the races and on the 3rd day of recovery to examine levels of muscle damage (creatine kinase and lactate dehydrogenase) and lymphocyte DNA damage (DNA in the tail, tail length, and tail moment). [Results] Serum creatine kinase, serum lactate dehydrogenase, and tail moment were significantly higher after the races compared with before the races in all groups. In addition, the 42 km group showed significantly higher levels of creatine kinase, lactate dehydrogenase, and tail moment than the 10 km and 21 km groups after the races. [Conclusion] Strenuous endurance exercise can cause muscle and lymphocyte DNA damage, and the extent of such damage can increase as running distance increases.

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We propose a novel HMI UI/UX for an in‐vehicle infotainment system. Our proposed HMI UI comprises multimodal interfaces that allow a driver to safely and intuitively manipulate an infotainment system while driving. Our analysis of a touchscreen interface–based HMI UI/UX reveals that a driver's use of such an interface while driving can cause the driver to be seriously distracted. Our proposed HMI UI/UX is a novel manipulation mechanism for a vehicle infotainment service. It consists of several interfaces that incorporate a variety of modalities, such as speech recognition, a manipulating device, and hand gesture recognition. In addition, we provide an HMI UI framework designed to be manipulated using a simple method based on four directions and one selection motion. Extensive quantitative and qualitative in‐vehicle experiments demonstrate that the proposed HMI UI/UX is an efficient mechanism through which to manipulate an infotainment system while driving.

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