Parentification refers to parent-child role reversal wherein the child adopts the parent's role instrumentally or emotionally. This role reversal practice between the parent and the child is not uncommon in certain cultures. The cultural dynamics and familial obligations at play have positive and negative outlooks with varying effects. This study focused on the effects of instrumental parentification experiences on psychological resilience and interpersonal relationships among selected Filipino young professional daughters during the COVID-19 pandemic.  Using purposive sampling, 19 Filipino young professional daughters from Metro Manila, Philippines, were selected for the study. Online interviews were conducted and thematic analysis was employed to process the data. Findings showed that most of the daughters, with “utang na loob” (indebtedness) value system, wholeheartedly accepted instrumental parentification. Thus, more tasks and responsibilities were shouldered by them due to the COVID-19 lockdown wherein older parents need to stay at home due to the fear of contracting the disease. Almost all shared that the COVID-19 pandemic tested their parent-child relationship. A few expressed that it made them let go of personal growth opportunities and experienced problems with their parents' relationship, given the uncertainties brought by the COVID-19 pandemic. Nevertheless, they shared that they could not leave their ageing parents in this time of COVID-19 pandemic and that with proper balancing of tasks and responsibilities at home and at work, parentification made them to become more self-reliant, mature faster, and responsible daughters.