Skin is the body is the largest organ and is the protective covering of the body. It is responsible for the normal functions like protection of the organs, healthy maintenance of the body and shaping and stretching. The skin is exposed to various types of stress like allergy-causing agents, disease-causing microorganisms etc. Medicinal plants are valuable resources that are known to the man from many generations that promote beauty and health. They are called as cosmeceuticals. These have various chemical constituents that promote beauty by reducing the acnes and killing the bacteria that causes and grow in the acnes. Anti-acne gels were prepared using the ethanol extracts of the plant Tulsi and Need incorporating the tea tree oil as a standard antioxidant. These were prepared, and the pH of the formulations was almost neutral to the skin and are stable in a stress test too. The anti-bacterial property of the gels was investigated in two methods, disc diffusion and turbidity method. The results showed a better activity of the formulations compared with tulsi and the standard antibiotic drug.
Franceschetti-Goldenhar syndrome or Goldenhar syndrome, also known as facio-auricular-spectrum (FAV), first and second branchial arch syndrome, or Oculo-Auriculo-Vertebral (OAV) spectrum is a rare congenital malformation which encompasses various morphological and functional abnormalities. The incidence of Goldenhar syndrome has been reported between 1:3500 to 1:5600 children, with a male: female ratio of 3:23. The incidence is higher, about 1 in 1000 children with congenital deafness. The exact etiology is not known. However, it is possible that abnormal embryonic vascular supply, disrupted mesodermal migration or some other factors leads to defective formation of the brachial and vertebral system. Most of the cases have been sporadic. Autosomal dominant, autosomal recessive and multifactorial modes of inheritance have also been suggested. Chromosomal studies have not revealed any abnormality. Authors report a case of a neonate with hemifacial microsomia, bilateral cleft lip and cleft palate, right deformed pinna, right facial palsy, single umbilical artery and congenital heart disease.
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