BackgroundThe extraction of physiological rhythms from electroencephalography (EEG) data and their automated analyses are extensively studied in clinical monitoring, to find traces of interictal/ictal states of epilepsy.MethodsBecause brain wave rhythms in normal and interictal/ictal events, differently influence neuronal activity, our proposed methodology measures the contribution of each rhythm. These contributions are measured in terms of their stochastic variability and are extracted from a Short Time Fourier Transform to highlight the non–stationary behavior of the EEG data. Then, we performed a variability–based relevance analysis by handling the multivariate short–time rhythm representation within a subspace framework. This maximizes the usability of the input information and preserves only the data that contribute to the brain activity classification. For neural activity monitoring, we also developed a new relevance rhythm diagram that qualitatively evaluates the rhythm variability throughout long time periods in order to distinguish events with different neuronal activities.ResultsEvaluations were carried out over two EEG datasets, one of which was recorded in a noise–filled environment. The method was evaluated for three different classification problems, each of which addressed a different interpretation of a medical problem. We perform a blinded study of 40 patients using the support–vector machine classifier cross–validation scheme. The obtained results show that the developed relevance analysis was capable of accurately differentiating normal, ictal and interictal activities.ConclusionsThe proposed approach provides the reliable identification of traces of interictal/ictal states of epilepsy. The introduced relevance rhythm diagrams of physiological rhythms provides effective means of monitoring epileptic seizures; additionally, these diagrams are easily implemented and provide simple clinical interpretation. The developed variability–based relevance analysis can be translated to other monitoring applications involving time–variant biomedical data.

A large proportion of cardiovascular diseases might be preventable, however, majority of this diseases occurs in rural areas where there is a poor presence of cardiologists. To overcome this issue, the use of wearable devices within the telemedicine framework would be of benefit. However, implementation of processing algorithms in smart-phones at mobile environments imposes restrictions ensuring high measurement quality of acquired ECG data, while maintaining low computation burden. This work presents an algorithm for scoring the quality of measured ECG recordings is developed. Particularly, a quality score is provided that takes into account the proportional correlation observed in acceptable signals based on a diversity scheme, and their inverse relation with standard deviation. Testing of proposed algorithm is carried out upon two different databases, the first one is of own production, while the second one is obtained from Physionet. As a result, high values of sensitivity and specificity are achieved.

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