A 42-year-old female, who worked as a full-time secretary for 15 years, was referred by her family physician to the neurology department with persistent pain, increasing numbness, and tingling in her right wrist and hand. The symptoms started intermittently some months prior, and worsened in the last 3 weeks. The pain and tingling increased in intensity during wrist flexion, and radiated to the first three fingers, and occasionally to the fourth. At the time of consultation, she was unable to grip or hold objects with her right hand. She did not recall any direct trauma to the wrist, and had no history of systemic disease or inflammatory disorders. She had no fever or other signs of infection, and had not traveled out of the country for at least 5 years. On physical examination, there was no swelling, discoloration, or scars. Pain and tingling were reproducible by wrist
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