Background and Purpose: Chronic musculoskeletal injuries are more common in cricket players. Acute problems may be due to trauma or injuries during sporting. The musculoskeletal system includes muscles, joints, bones, cartilage, ligaments, fascia, nerves and other associated soft tissues. Whatever the mode of injury, it causes pain, movement restriction, muscle weakness, and ultimately loss of functions. Anthropometric variables of each player in cricket will also influence the occurrence of problems. The current study focused on identifying the most common site involved in musculoskeletal problems and to explore possible variations in anthropometric characteristics. Methodology: This study was conducted in Kuala Lumpur, Malaysia where Asian Cricket Council Premier League 2014 was conducted. Permission to approach the players was taken from the council members and all the players were assured that the information collected from them will be kept confidential and all were explained about the objective study. Modified Nordic musculoskeletal questionnaire was distributed to the players and instructions were given about how to fill the questionnaire. Their anthropometric characteristics, experience and time of training sessions were collected by a blinded assessor. Results: Player's height (p = 0.003), weight (p = 0.050), experience (p = 0.001) and practicing hours per week (0.002) were analyzed. There is a statistically significant difference in these characteristics was observed. Occurrence of acute troubles (within 7 days) of upper back and elbow region were found different in four teams with a P value of 0.007 and 0.022 respectively. Persistence of neck, shoulder and lower back troubles in the last one year has a significant difference between the groups with a P value of 0.014, 0.003 and 0.021 respectively. Conclusion: This study can conclude that the prevalence of musculoskeletal injuries is more in cricket. Especially shoulder, neck, lower limbs and lower back. The incidence of acute problems is more in elbow and upper back regions. This may be acute injuries but not due to chronic over use. The anthropometric variations between groups participated in ACC premier league, Malaysia 2014 was also significantly differing from each other.