In the present day and age, engineered materials are making significant strides in their application in the biomedical sector. Human implants have piqued the interest of material and metallurgy researchers due to their unique properties. Machining the materials into implants customized for individual patients has been the standard practice nowadays. To contribute further to the same area, the current research work aims to investigate the machinability of T-L107.12 (a titanium-based human implant) using a non-traditional method called wire electrical discharge machining (WEDM). The machinability of the machining process has been evaluated based on the material removal rate using a roughness meter and the atomic force microscope. The further impact of the machining parameters on the output responses was analyzed based on the statistical analysis.