chiatrie) were also searched. One report of neck dystonia related to quetiapine was found. Raja and Azzoni 3 reported a case of neck dystonia first with risperidone and later with quetiapine in one patient. The manufacturer of quetiapine (AstraZeneca) was contacted and stated that quetiapine-related neck dystonia is a very rare event, but was not aware of any published papers concerning quetiapine and neck dystonia or torticollis. As the event developed with monotherapy, other drug-related causes were ruled out. An alternative cause could have been idiopathic dystonia, which often appears to have a strong psychogenic component, but the course of the adverse drug reaction makes this explanation more unlikely. 4 This adverse event is considered probable according to the Naranjo probability scale. 5The frequency of extrapyramidal symptoms with second-generation antipsychotics seems to be lower than with first-generation antipsychotics. The same is true for quetiapine, although there are a few cases of tardive dyskinesia and acute dystonia related to quetiapine without any previous or questionable treatment with the first-generation agents. 6
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