Objective: The present study aimed to compare motor development of infants preterm samples from two regional Brazilian, using a reliable scale evaluation, to determine the influence that environmental context can have on infants exposed to perinatal conditions and similar risk factors. Methods: Two samples were used transverse infants with low birth weight: study group (SG = 70) and comparison group (CG = 43). The evaluation instrument used was the Alberta Infant Motor Scale (AIMS). Results: There were no statistically significant differences in total score on the AIMS, although they were no differences in the variables gestational age (at 2, 3 and 4 months) and birth weight (weight slightly larger than the GC) among infants. There was also a difference in the classification of motor development at 2 and 3 months of corrected age, according to the standard scale, in which GE was ranked as the latest GC. Conclusion: The results suggest that different regions of preterm infants exhibit the same trend in its motor, even if subjected to different environmental influences. It is suggested the extension of this study considering the more detailed control of the environment in which the infant is inserted, including maternal practices.