ObjectiveThe aim of the study was to evaluate the effects of a 28-day exposure to a 50 Hz electromagnetic field of 10 kV/m on the oxidative stress in selected rat central nervous system (CNS) structures. Material and Methods Twenty male Wistar rats served as experimental subjects. Ten rats were exposed to an electromagnetic field with a frequency of 50 Hz, intensity of 10 kV/m, and magnetic induction of 4.3 pT for 22 hours a day. The control group of ten rats was subject to sham exposure. Homogenates of the frontal cortex, hippocampus, brainstem, hypothalamus, striatum, and cerebellum were evaluated for selected parameters of oxidative stress. Results Following the four-week exposure to a low-frequency electromagnetic field, the mean malondialdehyde levels and total oxidant status of CNS structures did not differ significantly between the experimental and control groups. However, the activities of antioxidant enzymes in brain structure homogenates were decreased except for frontal cortex catalase, glutathione peroxidase, and hippocampal glutathione reductase. The low-frequency electromagnetic field had no effect on the nonenzymatic antioxidant system of the examined brain structures except for the frontal cortex. Conclusion The four-week exposure of male rats to a low-frequency electromagnetic field did not affect oxidative stress in the investigated brain structures.
Non-invasive electrotherapy it is a safe way to use electric current in physical therapy to treat pain related to musculoskeletal diseases. Electrotherapy mediated analgesia results from stimulation of pain inhibiting receptors activity increase as well endogenous opioids secretion rise. Physical therapy applies different modalities to ease the pain whereas transcutaneous electrical nerve stimulation (TENS) is one of them. The aim of this study was assessment of impact of transcutaneous electrical nerve stimulation on sensory threshold and threshold of pain. Study included 33 females and 30 males, healthy volonteers aged 21–25 years. In participants single convectional transcutaneous electrical nerve stimulation was performed. Sensory and pain threshold were assessed before stimulation, immediately after stimulation and in 15th and 30th minute after stimulation. Measurements were performed with PainMatcher device. The results have proved that single convectional TENS leads to sensory threshold decrease and increase of pain threshold. The research confirms positive effects of TENS in antinociceptic processes.
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