BackgroundPostoperative nausea and vomiting (PONV) is a common complication of pediatric anesthesia, but the overall incidence of PONV in patients undergoing adenoidectomy is unknown. The aim of this controlled study was to compare the effect of dexamethasone administration with placebo to reduce PONV in children undergoing endoscopic adenoidectomy under general anesthesia.Material/MethodsA randomized placebo-controlled study included 118 pediatric patients who underwent elective endoscopic adenoidectomy under general anesthesia. A dexamethasone-treated (0.15 mg/kg) group (Group D) (n=56) and a placebo group (Group C) (n=62) were randomly assigned. The incidence of nausea and vomiting was recorded on the day of surgery. Postoperative nausea was assessed according to illustrated Baxter Animated Retching Faces (BARF) scale. The Face, Legs, Activity, Cry, and Consolability (FLACC) scale (scores between 0–10) was used to assess pain. Follow-up was performed on the 14th postoperative day by a telephone call.ResultsOverall prevalence of postoperative nausea was 25% (30/118) and postoperative vomiting was 14% (17/118). In the first 24 hours following surgery, in Group D, the incidence of nausea and vomiting was 13% and 7%, respectively; in Group C, without pharmacological prophylaxis, the incidence of postoperative nausea and vomiting was 37%, and 21%, respectively.ConclusionsA prospective controlled study in children undergoing endoscopic adenoidectomy under general anesthesia showed that dexamethasone (0.15 mg/kg) significantly reduced the incidence of PONV without increasing the risk of postoperative hemorrhage. Dexamethasone is a safe method for the prevention of PONV that may be recommended in pediatric anesthesiology.

No abstract

Monitoring the depth of general anaesthesia (GA) enables the anaesthetist to reach the optimal depth of GA, and thus prevent the occurrence of too deep or too shallow anaesthesia, together with all associated consequences. Anaesthesia, which is too shallow, increases the risk of perioperative awareness. In adult patients, the incidence of perioperative awareness is 0.1-0.2 % for the total number of GA procedures,in paediatric population, the clinical studies present the incidence of up to 5 % (1973), 0.8 % (2005) for the total number of GA procedures. Perioperative awareness is a serious complication, with possible psychological consequences for the patients, including post-traumatic stress disorder.BIS monitoring is one of the possibilities how to assess the depth of GA. This technique is based on the assessment of EEG curve, when individual parameters of the EEG signal are, using mathematical methods, transformed into a dimensionless number, so-called bispectral index (BIS), the value of which is expressed on the scale from 0 to 100, and which reflects the depth of general anaesthesia.This prospective randomized clinical trial has proven, on a group of 101 children that the use of BIS monitor in the course of GA shortens the period of recovery from general anaesthesia, however, it does not decrease the consumption of inhalation anaesthetics when compared to GA performed without BIS monitoring. The results of the study confirmed the importance of monitoring the depth of GA in patients with intravenous administration of Propofol. The authors have observed an inverse linear relation between the values of BIS and MAC (minimum alveolar concentration).