This paper analyzes the automobile accessibility of Prague from the Czech territory over a 100-year period: from the creation of independent Czechoslovakia to the planned completion of an arterial network of motorways and high-speed roadways in 2020. Using publications containing information about the evolution of the road network in Czechia, we digitised historical maps and created geo-databases of the road infrastructure. We then produced accessibility models and performed accessibility analyses for four years – 1920, 1960, 2001 and 2020, using ArcGIS 9.3. These were compared and changes in accessibility were identified using cartographic tools.