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Galaxy is an open source web based framework for data intensive biomedical research. It is an environment for interactive analysis that transparently tracks the details of analyses, a workflow system for convenient reuse, data management, sharing and publishing of the results. In this paper we describe extending the Galaxy framework to the GARUDA Grid computing infrastructure for running bioinformatics applications on various grid. This involves developing a grid job adaptor for the Galaxy workflow. GARUDA grid is an aggregation of heterogeneous resources and advanced capabilities for scientific applications. Gridway is the metascheduler for running the jobs on the Garuda grid. Here we present the integration of Galaxy workflow with the Gridway middleware by developing a grid job runner to interface. This grid enabled galaxy facilitates computational biologists to perform complex problems on the grid environment through a web browser.

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