BACKGROUND Hydatid disease is one of the most common surgical conditions in Kurnool district of Andhra Pradesh. Ultrasonography is the initial investigation of choice in detecting and characterizing the disease. Ultrasound plays important role in selection of cases for surgery by ruling out secondary infection and other complications. METHODS The present study was done at Santhiram Medical College and General Hospital, from January 2016 to November 2018. Patients with suspected abdominal masses were screened with ultrasound to detect hydatid disease. Ultrasound diagnosis was correlated with lab tests and surgery findings. Post-operative follow-up was also done in some cases. During ultrasound, cyst characterisation was done. The present study consists of thirty-five cases of hydatid disease. Tehe study was done and analysed organ wise. Multiplicity of cysts was noted. RESULTS Out of 35 cases, 21 were males and 14 were males. Organ wise distribution showed 28 cases in liver, 3 cases in spleen, one case in kidney, 2 cases in peritoneal cavity and one in the retroperitoneum. More cases were seen in 4 th and 5 th decades by age wise distribution. CONCLUSIONS Ultrasound is non-invasive, simple and inexpensive modality and is very sensitive for detection of hydatid disease.