Aim
To report the reproductive results and symptomatic relief of patients with adenomyosis who attempted to conceive after ultrasound‐guided radiofrequency ablation (RFA).
Methods
Of 182 consecutive patients with adenomyosis who had undergone RFA, only 81 patients were eligible for this study. Pregnancy outcomes, postoperative complications, preoperative and postoperative pictorial blood loss assessment chart scores, and pain scores were evaluated.
Results
Of these 81 patients, 74 were infertile and seven were single at the time of RFA. The mean age at the time of operation was 35.8 years. The mean duration from the time of RFA to conception was 18.9 months (range, 2–72 months). Fifty‐nine patients tried natural conception, while 22 patients attempted conception with assisted reproductive techniques. Twenty‐nine (35.8%) patients achieved 39 pregnancies. Except for the 23 patients who did not actively try to conceive and who inevitably or arbitrarily discontinued pregnancy attempts, the pregnancy success rate reached 50%. Twenty‐two (84.6%) of the 29 patients delivered 24 (66.7%) live babies (nine vaginal deliveries and 15 cesarean sections). Twelve (33.3%) pregnancies ended in spontaneous abortions. No uterine ruptures occurred. Paired sample t‐tests revealed that preoperative pictorial blood loss assessment chart and pain scores were significantly (P < 0.05) different from the postoperative scores at 1‐, 3‐ and 6‐months.
Conclusion
RFA could be considered a minimally‐invasive treatment option for patients with adenomyosis who desire to maintain fertility and alleviate symptoms.
In this work the effect of white-rot fungi, A. biennis, C. unicolor, T. versicolor and G. odoratum, and 2,5-dimethylaniline induced extracellular laccase on the transformation of chlorinated pollutants, pentachlorophenol (PCP) and 2-chlorophenol (2CP), was examined.
SummaryThe effects of pentachlorophenol (PCP) and 2-chlorophenol (2CP) on white rot fungi, Abortiporus biennis, Cerrena unicolor, Gloeophyllum odoratum, and Trametes versicolor were investigated. With the exception of C. unicolor and A. biennis, concentrations of PCP higher than 50 ppm inhibited fungal growth completely. However, extreme concentrations of PCP (500 ppm) caused a 61 % increase in growth of C. unicolor compared to the control culture within 14 days. When initial PCP concentrations were 50 ppm A. biennis and C. unicolor achieved, respectively, 87 % and 78 % of chlorophenol transformation within 3 days. However, when 2,5-dimethylaniline (0.2mM) was added to the C. unicolor culture, 98 % of PCP transformation was achieved after one hour. Under the same conditions, A. biennis transformed 44 % of PCP. Both chlorophenols are completely removed, when laccase activity reaches its maximum. In conclusion, among the four fungi investigated, C. unicolor and A. Biennis were very effective in transforming PCP and 2-CP. This biotransformation was greatly intensified by 2,5-dimethylaniline and accompanied by an increase in laccase activity.
KeywordsLaccase 2,5-Dimethylaniline Abortiporus biennis Cerrena unicolor Gloeophyllum odoratum Trametes versicolor White-rot fungi Pentachlorophenol 2-Chlorophenol Brought to you by | HEC Bibliotheque Maryriam ET J.
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