An integer of the form P 8 pxq " 3x 2´2 x for some integer x is called a generalized octagonal number. A quaternary sum Φ a,b,c,d px, y, z, tq " aP 8 pxq`bP 8 pyq`cP 8 pzq`dP 8 ptq of generalized octagonal numbers is called universal if Φ a,b,c,d px, y, z, tq " n has an integer solution x, y, z, t for any positive integer n. In this article, we show that if a " 1 and pb, c, dq " p1, 3, 3q, p1, 3, 6q, p2, 3, 6q, p2, 3, 7q or p2, 3, 9q, then Φ a,b,c,d px, y, z, tq is universal. These were conjectured by Sun in [11]. We also give an effective criterion on the universality of an arbitrary sum a 1 P 8 px 1 q`a 2 P 8 px 2 q`¨¨¨`a k P 8 px k q of generalized octagonal numbers , which is a generalization of "15-theorem" of Conway and Schneeberger.2000 Mathematics Subject Classification. Primary 11E12, 11E20.