Lipoatrophia semicircularisa distinct entity? Dear Editor, Lipoatrophia semicircularis (LS) is a localized lipodystrophy of the subcutaneous fat tissue characterized by horizontal semicircular band-like depressions. 1 LS appears most frequently unilateral or bilateral on the anterior and lateral sides of the thighs. 1 In general, LS is clinically asymptomatic and the overlying skin and the underlying muscle tissue inconspicuous. The mean age of affected individuals is around 40 years with a female preponderance. 1,2 We present the case of pressure-induced LS and investigation of the histopathological changes. A 30-year-old woman in her 16th week of pregnancy presented with a 5-day history of an isolated horizontal indentation on her lateral right thigh (Fig. 1a). The overlying skin showed no signs of induration, discoloration, or inflammation. The patient denied antecedent trauma, injections, or concomitant comorbidities. However, she reported leaning against the , MD

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