ObjectiveCervical cancer is one of the most frequent malignant diseases diagnosed during pregnancy. Abdominal or vaginal radical trachelectomies are fertility-preserving alternatives to radical hysterectomy for young women with early-stage cervical cancer that can be performed during ongoing pregnancy.MethodsA literature review of articles on this subject was conducted through a Medline search for articles published in English or French.ResultsAt this moment, 21 cervical cancer patients, including ours (4 stage IA2, 16 IB1, and 1 IB2) who underwent radical trachelectomy during pregnancy have been reported. Of these, 10 were performed by vaginal route and 11 were abdominal radical trachelectomies.ConclusionsRadical trachelectomy could be offered as an option for pregnant patients with early invasive cervical cancer. It may help women avoid the triple losses of a desired pregnancy, fertility, and motherhood.

Introduction:Abdominal radical trachelectomy (ART) for tumors of the uterine cervix can be performed while the pregnancy is ongoing, but the success rates so far are reduced.Case series presentation:ART was performed in three patients with cervical cancer diagnosed during pregnancy, with a triple aim to offer a radical surgery for cervical cancer, but also to preserve the ongoing pregnancy and fertility. The ART was successful in one patient, and she delivered a healthy baby at term, by cesarean section. The other 2 patients experienced obstetrical complications and lost their pregnancies after ART, but in one of the cases, fertility was preserved.Conclusions:Radical trachelectomy could be performed as alternative therapy for pregnant women with invasive malignancies of the cervix. This procedure may prevent female patients to lose a much-desired pregnancy, their fertility, as well as their maternity.

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Despite the available effective screening techniques, cervical cancer is the most common genital malignancy in Romania. In patients with isolated pelvic recurrence after radiotherapy, exenteration represents the only chance for curative treatment. We present the case of a 45-year-old patient with a massive pelvic tumour causing intensive, poorly controlled vaginal bleeding, bilateral hydronephrosis and chronic renal failure. She underwent total infralevatorian exenteration with vulvectomy. Postoperative recovery was uneventful, and she presented a good evolution in the two months following surgery. We consider pelvic exenteration as the last treatment option to cure irradiated pelvic tumour recurrences. CASE REPORTWe present the case of a 45-year-old patient who was diagnosed with stage IIB squamous cervical carcinoma, complaining of atypical vaginal bleeding. She was referred to chemo-radiotherapy with curative intent. After five years she relapsed, complaining of lower abdominal pain and vaginal bleeding. Transrectal ultrasound (Figure 1) and magnetic resonance scan revealed a tumor of 8 × 4 cm, invading the parametrium bilaterally, the urinary bladder, the rectum, vagina, distal urethra, and the right internal iliac vessels. No distant metastases were described. The patient developed bilateral hydronephrosis with a nonfunctional right kidney. In September 2016, the patient had been admitted for intensive vaginal bleeding in order to attempt hemostasis and for blood transfusions.