Objective To evaluate the correlation of the maximum six minutes of daily activity (M6min) with standard measures of functional capacity among older adults with heart failure (HF) in comparison to younger subjects and its prognostic utility. Design Prospective, cohort study. Setting Tertiary care, academic HF center. Participants Sixty, ambulatory, adults, NYHA Class I-III, stratified into young (51±10 years) and older cohorts (77±8 years). Intervention Continuous actigraphy monitoring on the non-dominant wrist. Measurements Correlation between M6Min and measures of functional capacity (6 minute walk distance; 6MWT) and with peak VO2 by cardiopulmonary exercise testing in a subset. Survival analysis was employed to evaluate the association of M6Min with adverse events. Results Compliance with actigraphy was high (90%) and did not differ by age. The correlation between M6min and 6MWT was higher in subjects ≥ 65 years of age than those <65 years of age (r=0.702, p=0.0002 vs. r=0.490, p=0.002). M6min was also significantly associated with peak VO2 (r=0.612, p=0.006). During the study, 26 events occurred (2 deaths, 10 hospitalizations, 8 emergency room visits and 6 intercurrent illnesses). The M6min was significantly associated with subsequent events (Hazard ratio of 2.728; 95% CI: 1.099–6.775, p=0.031) independent of age, gender, ejection fraction, NYHA class, brain natriuretic peptide, and 6MWT. Conclusions The high compliance with actigraphy and association with standard measures of functional capacity and independent association with subsequent morbid events suggests that it may be a useful for monitoring older adults with heart failure.
Peer support is integral to a variety of approaches to alcohol and drug problems. However, there is limited information about the best ways to facilitate it. The “social model” approach developed in California offers useful suggestions for facilitating peer support in residential recovery settings. Key principles include using 12-step or other mutual help group strategies to create and facilitate a recovery environment, involving program participants in decision making and facility governance, using personal recovery experience as a way to help others, and emphasizing recovery as an interaction between the individual and their environment. Although limited in number, studies have shown favorable outcomes for social model programs. Knowledge about social model recovery and how to use it to facilitate peer support in residential recovery homes varies among providers. This paper presents specific, practical suggestions for enhancing social model principles in ways that facilitate peer support in a range of recovery residences.
Background Anergia (lack of energy) is a newly delineated, criterion-based geriatric syndrome. Since heart failure (HF) is a common chronic condition among older adults and a since a cardinal symptom of HF is reduced energy, we characterized the degree of anergia in subjects with HF and evaluated its relevance to disease severity, functional performance and quality of life. Methods Prospective 3-month cohort study among a convenience sample of 61 subjects (61±15 years, 48% women, EF 41±16%) with NYHA Class I-III HF were studied. The criterion for anergia was based upon the major criterion “sits around for lack of energy” and any two of six minor criteria. Principal measures in addition to demographic and clinical characteristics included functional performance (NYHA class, 6 minute walk, cardiopulmonary exercise testing), plasma B-type natriuretic peptide and quality of life (SF-12 and Minnesota Living with Heart Failure Questionnaire). To evaluate the relevance of anergia to daily function, each subject wore an actigraph, a watch-like wrist device that continuously and automatically monitors patient activity levels and energy expenditure, for 3 months. Results Anergia was prevalent in 39% of this population. Anergia was associated with decrements in functional capacity (higher NYHA class and lower six minute walk distance) as well as reduction in quality of life but was not associated with ejection fraction. Actigraphy data demonstrated that HF subjects with anergia spent significantly less time performing moderate physical activity and the peak activity counts per day were significantly lower than HF subjects without anergia. Additionally, the amplitude of circadian rhythm was lower, suggesting altered sleep and activity patterns in HF subjects with anergia compared to those without anergia. Over the 3 months of follow-up, there was a significant association between anergia and inter-current hospitalization. Conclusions Anergia is significantly associated with several of the cardinal domains of heart failure. Its presence is associated with demonstrable differences in both physical activity and circadian rhythm as measured by actigraphy and an increased risk of hospitalizations. Accordingly, anergia may be a target for intervention among heart failure subjects.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.