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conduit, complications, adjunctive procedures, limb salvage, and patient survival data after thrombolysis. If any of these were not available, the patient was excluded.Results: We reviewed >500 bypasses, but 58 bypasses met criteria (60.3% were vein); most patients were male (62%) and had a femoral to popliteal (50%) bypass. There was no difference in comorbidities between the groups. In most cases, we achieved complete lysis and 98% technical success. The majority required an adjunctive procedure at the end of lysis, mostly angioplasty (88%). The hazard of subsequent graft failure after successful thrombolysis for prosthetic bypass grafts is 74% reduced compared with the hazard of graft failure for autogenous vein bypass grafts, and this result is statistically significant (P < .01; Fig; Table ). However, there was no difference in amputation rates between the groups or time to death over time.Conclusions: Thrombolysis for vein and prosthetic bypasses can be achieved with acceptable graft patency and limb salvage. Vein bypass might need closer surveillance, particularly the first 6 months, to improve patency after successful thrombolysis.

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