Background: Celiac disease (CD) is a genetically determined gluten-sensitive enteropathy resulting in nutrient malabsorption, can have extra gastrointestinal tract (GIT) presentations, short stature may be the only presenting clinical feature, even in the absence of gastrointestinal symptoms. The aim and objective of this study was toMethods: This cross-sectional study was performed on 1000 children between ages 5 to 10 year of different schools, in Jaipur, district of Rajasthan. An anthropometric measurement (height, weight) was done for all children. Serum samples were analyze for IgA antibodies to human tissue transglutaminase (tTG) with lower detection limit of 1.0 U/ml and 15 U/ml. Positive samples for tTG antibodies were reanalyzed human endomysial autoantigens (EmA).Results: Out 1000 children screened, six were seropositive, of those four were females and two were males. The serological proportion of CD in this population was 1:166. These Six seropositive group tends to have lower height, weight than the seronegative group, but the difference was only significant for height (P=<0.01).Conclusions: Although gastrointestinal manifestations are important presentation of celiac disease, nevertheless short stature alone or in combination with other symptoms of celiac disease has been present.

Background: To study clinical presentations and complications of P. vivax malaria Methods: A prospective hospital-based clinical observational study was conducted on 100 patients under age of 14 years were enrolled in the study. Result: The most common presentation was fever followed by pallor. Among the total of 100 cases studied 2 cases died with a case fatality rate of 2%. Among the total of 100 cases studied 5 cases (10%) required ICU admission. Conclusion: P. vivax monoinfection tends to have severe complications in children. There is a need to review severity criteria for P. vivax malaria. Keywords: Vivax, Fever, ICU

Background: This study to find out the prevalence of diabetic retinopathy (DR) among diabetic children with type 1 DM treated with insulin. Methods: This is a cross-sectional study conducted on 50 children with type 1 DM from 1 to 14  years of age. All patients were subjected to full fundus examination and were then classified according to its results into patients with DR and patients without DR. Results: A total of 6 (12.0%) patients were found to have DR. 5 patients had retinopathy in one eye and 1 patients had retinopathy in both eyes. Thus, the total number of eyes with retinopathy was 7 of 100 screened eyes (7.00% of all eyes). Most eyes with retinopathy had a mild degree of NPDR, as it was present in 6 eyes. The other 1eyes had moderate degree of retinopathy Conclusion: The prevalence of DR was 12.0% among all studied patients and 7.00% among all studied eyes. The grade of retinopathy was directly related to the duration of DM, fasting blood glucose, and glycosylated hemoglobin levels. Keywords: DM, DR, Hb1Ac

Background: The aim of the study was to study the clinical profile, laboratory parameters of enteric fever cases in pediatric age group. Methods: This was a prospective study carried on Pediatric patients aged 1 to 14 years with clinically suspected enteric fever (fever for 5 days or more with no primary focus on clinical examination) and proven either by positive blood culture or Widal test with significant titre (level of both H or O antibodies of 1 in 160 dilution or more by tube method) were enrolled in the study. Results: The mean white blood cell (WBC) count was 8256.32±1236.12 cells/cumm. Out of 100 patients, 73(73.00%) had WBC count within the normal range (4000-11000 cells/cumm). 3(3.00%) had leucopenia, while 24(24.00%) had leucocytosis. 4(4.00%) patients had thrombocytopenia Conclusions: Enteric fever is major cause of febrile illness in children (especially school going). Fever with abdominal pain, vomiting and diarrhea were major clinical manifestations. There was 100% sensitivity to ceftriaxone, which was highly effective as monotherapy. Keywords: WBC, Typhoid, Clinical profile.

: Jaundice is the commonest abnormal finding with an incidence of about 60% in term babies and 80% in preterm babies. It is the commonest cause of admission to hospitals in the newborn period. In preterm babies, the percentage is exceedingly high due to their physiological handicaps and other hazards of prematurity like Asphyxia, septicemia, respiratory and circulatory Insufficiency. Non-physiological or pathological jaundice is also known to occur in (8-9)% of newborns. Its timely detection and optimal management are crucial to prevent brain damage and subsequent neuro-motor retardation. Aims of this study to find out the etiology of jaundice in neonates, admitted in neonates unit attached to SMS medical college Jaipur.Method: This Observational study was conducted in Neonatal Intensive Care Unit (NICU) and Post Natal Ward attached to SMS medical college Jaipur, after approval from the hospital ethical committee, over a period of 12 months(October 2011 to September 2012. Study was carried on 500 neonates presenting clinically with neonatal hyperbilirubinemia.Result: The onset of jaundice was seen maximum between live hour 24-72 hours (n=290, 58% cases), followed by live hour 72 hours-14 days (n=160, 32%). At more than 2 weeks there was only 3 case (0.6%). The etiological factors in the causation of jaundice in the decreasing order of frequency were exaggerated physiological jaundice accounts for (28%), ABO-incompatibility (24.4%), Rh-incompatibility (13.8%), Idiopathic (10.4%), cephalhematoma (10.2%), septicemia (6%), intrauterine infections (4%), BMJ (1.8%), Galactocemia (0.8%) and G6PD  Deficiency (0.6%) respectively.Conclusion: Hyperbilirubinemia is more severe in newborns, therefore precautionary measure should be adopted by both parents, and clinicians to diagnose and treat the diseases properly.