Hypertension is the leading single preventable risk factor for cardiovascular disease. The India Hypertension Control Initiative (IHCI) project was designed to improve hypertension control in public sector clinics. The project was launched in 2018–2019 in 26 districts across five states: Punjab (5), Madhya Pradesh (3), Kerala (4), Maharashtra (4), and Telangana (10), with five core strategies: standard treatment protocol, reliable supply of free antihypertensive drugs, team-based care, patient-centered care, and an information system to track individual patient treatment and blood pressure control. All states implemented simple treatment protocols with three drugs: a long-acting dihydropyridine calcium channel blocker (amlodipine), angiotensin receptor blocker (telmisartan), and thiazide or a thiazide-like diuretic (hydrochlorothiazide or chlorthalidone). Medication supplies were adequate to support at least one month of treatment. Overall, 570,365 hypertensives were enrolled in 2018–2019; 11% did not have follow-up visits in the most recent 12 months. Clinic-level blood pressure control averaged 43% (range 22–79%) by Jan-March, 2020. The proportion of the estimated people with hypertension who had it controlled and documented in public clinics increased three-fold, albeit from very low levels (1.4–5.0%). The IHCI demonstrated the feasibility of implementing protocol-based hypertension treatment and control supported by a reliable drug supply and accurate information systems at scale in Indian primary health care facilities. Lessons from the IHCI’s initial phase will inform plans to improve screening in health care facilities, increase retention in care, and ensure a sustained supply of drugs as part of a nationwide hypertension control program.

No abstract

Novel bis ester namely I , 1 '-(1-methylethylidene) bis[4-( 1-( 1 -imino-l-ethyl benzoate)-2-propanolyloxy]benzene was prepared by the reaction of epoxy resin, diglycidyl ether of bisphenol-A-(DGEBA) and 4-amino ethyl benzoate. The polyamides (PAS) were prepared by the condensation of bis ester derivative with various aliphatic diamines viz., 1 .Zethylene diamine (EDA), 1,3-propylene diamine (PDA), 1 ,Cbutylene diamine (BDA) and 1,6-hexamethyIene diamine W D A ) . The resultant novel epoxy resin based PAS were characterized by infrared spectroscopy and number average molecular weight ( a n ) . As produced, polyamides may act as epoxy curing agent, the kinetic study of the PA-epoxy resin system has been established by differential scanning calorimetty (DSC) and the kinetic parameters have been evaluated. Neat PA-epoxy cured products have also been characterized by thermogravimetric analysis (TGA).KEY WORDS 4-amino ethyl benzoate epoxy resin, polyamides, aliphatic diamines. thermogravimetric analysis.

SynopsisThe glass fiber-epoxy composites were fabricated with the E-type glass cloth and diglycidyl ether of bisphenol A (DGEBA) using 12% diethylenetriamine (DETA) as catalyst on the basis of DGEBA. The properties were modified by incorporating diluents such as epoxidized 2,2,6,6-tetramethylolcyclohexanol (ETMC) and 1,4-butandioldiglycidyl ether (BDDE) with/without 20 parts per 100 g of a condensation product of phenyglycidylether and 4-hydroxyacetanilide (PGEHA) employed as fortifier. The characterization of these epoxy laminates includes resistance to chemical reagents, dynamic mechanical analysis, and mechanical properties like flexural strength, impact strength, and hardness. The dielectrical properties such as breakdown strength, dielectric constant ( d ) , dielectric loss (c"), and loss tangent (tan6) were estimated.

Background: In India, the traditional drugs like opium, charas, bhang and ganja were used by sections of the society partly as leisure time activity and partly as part of the religious ceremony. Therefore, their consumptions did not invite much negative sanction from the society. The addictive potential of a drug varies from substance to substance, and from individual to individual. Dose, frequency, pharmacokinetics of a particular substance, route of administration, and time are critical factors for developing a drug addiction. Aims & Objective: (1) To identify the socio-demographic characteristics of the substance abusers; (2) To identify the substances commonly used other than tobacco; (3) To identify the effects of positive family history on starting the substance. Material and Methods: Interview based Cross-Sectional study was conducted among Substance abusers who were attending De-addiction centres "Naya Jivan Vyasan Mukti Kendra, Ahmedabad" Results: Substance abuse was commonly seen in the age group of 25-45 years (66.3%) and also in class IV and V (69.0%). Only males were found to get treatment in de-addiction centre for various addiction and 80.6% of them were married. 58.3% Substance abusers (58.3%) were living in nuclear families. Substance abuse was higher (75.8%) in less educated people (secondary or below). Age of initiation of substance was below 30 years of age (86.1%). Mean age for starting substance was 23.96 + 6.96 years. Commonly abused substances for which patients were coming to deaddiction centre were Alcohol (62.1%), Cannabis (13.6%), Brown sugar (13.6%), Alprazolam (2.9%), Cough syrup (1.9%), White Ink (2.9%). Friends were mostly responsible for initiating the substance abuse (81.6%). Headache (12.6%), vertigo (11.7%) and insomnia (11.7%) were most common presenting symptoms seen in substance abusers. Conclusion: The mean age of initiation of substance abuse was early twenties. Alcohol addiction was significantly associated with the positive family history of alcohol intake (p value <0.0001). Commonly abused substances for patients which were coming were Alcohol (62.1%), Cannabis (13.6%) etc.