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The title compound, C 7 H 6 Br 2 N 2 O, was obtained from a condensation reaction of 3,5-dibromo-2-hydroxybenzaldehyde and hydrazine hydrate. The molecule is approximately planar, the largest deviation from the mean plane through all of the non-H atoms being 0.053 (1) Å . The molecular conformation is stabilized by an intramolecular O-HÁ Á ÁN hydrogen bond, generating an S(6) ring motif. In the crystal, intermolecular N-HÁ Á ÁBr and N-HÁ Á ÁO hydrogen bonds link the molecules, forming chains parallel to the b axis. Molecules are further linked by -stacking interactions, with centroid-centroid distances of 3.925 (3)-3.926 (3) Å , forming a three-dimensional network.

Schiff base cobalt complexes are usually studied for their potential, through interaction with DNA, as probes for nucleic acid structure, and as chemotherapeutic agents, and anticancer drugs. Kinetically inert cobalt(III) compounds are of particular interest because when subjected to biologically reducing environments they are converted to kinetically labile Co(II) derivatives, providing the means for the delivery of NNO and N2O2 donor ligands to specific locations, e.g. cytotoxins to certain solid tumors. It is noted that complexes with p-tBu substituents are expected to have greater lipophilicity than the p-Me derivatives which could lead to increased bioavailability, better tissue and cell penetration and increased permeability. At the meeting, we are planning to discuss the precise crystal structures of Co(III) complexes derived from 4-tert-butyl-2,6dibenzoylphenol and various diamines and their interaction with calf thymus (CT) DNA.