Background: According to the ventricular myocardial band model, the diastolic isovolumetric period is a contraction phenomenon. Our objective was to employ speckle-tracking echocardiography (STE) to analyze myocardial deformation of the left ventricle (LV) and to confirm if it supports the myocardial band model. Methods: This was a prospective observational study in which 90 healthy volunteers were recruited. We evaluated different types of postsystolic shortening (PSS) from an LV longitudinal strain study. Duration of latest deformation (LD) was calculated as the time from the start of the QRS complex of the ECG to the latest longitudinal deformation peak in the 18 segments of the LV. Results: The mean age of our subjects was 50.3 ± 11.1 years. PSS was observed in 48.4% of the 1620 LV segments studied (19.8%, 13.5%, and 15.1% in the basal, medial, and apical regions, respectively). PSS was more frequent in the basal, medial septal, and apical anteroseptal segments (>50%). LD peaked in the interventricular septum and in the basal segments of the LV. Conclusions: The pattern of PSS and LD revealed by STE suggests there is contraction in the postsystolic phase of the cardiac cycle. The anatomical location of the segments in which this contraction is most frequently observed corresponds to the main path of the ascending component of the myocardial band. This contraction can be attributed to the protodiastolic untwisting of the LV.

BackgroundLeft ventricular ejection fraction (LVEF) results from the combined action of longitudinal and circumferential contraction, radial thickening, and basal and apical rotation. The study of these parameters together may lead to an accurate assessment of the cardiac function.MethodsNinety healthy volunteers, categorized by gender and age (≤ 55 and >  55 years), were evaluated using two-dimensional speckle tracking echocardiography. Transversal views of the left ventricle (LV) were obtained to calculate circumferential strain and left ventricular twist, while three apical views were obtained to determine longitudinal strain (LS) and mitral annular plane systolic excursion (MAPSE). We established the integral myocardial function of the LV according to: 1. The Combined Deformation Parameter (CDP), which includes Deformation Product (DP) - Twist x LS (° x %) - and Deformation Index (DefI) -Twist / LS (° / %)-; and 2. the Torsion Index (TorI): Twist / MAPSE (° / cm).ResultsThe mean age of our patients was 50.3 ± 11.1 years. CDP did not vary with gender or age. The average DP was − 432 ± 172 ° x %, and the average DefI was − 0.96 ± 0.36 ° / %. DP provides information about myocardial function (normal, pseudonormal, depressed), and the DefI quotient indicates which component (s) is/are affected in cases of abnormality. TorI was higher in volunteers over 55 years (16.5 ± 15.2 vs 13.1 ± 5.0 °/cm, p = 0.003), but did not vary with gender.ConclusionsThe proposed parameters integrate values of twisting and longitudinal shortening. They allow a complete physiological assessment of cardiac systolic function, and could be used for the early detection and characterization of its alteration.

Background: The purpose of this work was to determine the influence of myocardial wringing on ventricular function in patients with cardiac amyloidosis (CA).Methods: Fifteen healthy volunteers (group 1) and 34 patients with CA (17 with left ventricular ejection fractions [LVEFs] $ 53% [group 2] and 17 with LVEFs < 53% [group 3]) were evaluated using two-dimensional speckletracking echocardiography. A control group of mass-matched patients (n = 20) with left ventricular (LV) hypertrophy and LVEFs $ 53% was also included. Longitudinal strain (LS), circumferential strain, and LV twist and torsion were calculated. Deformation index (DefI), a new parameter of wringing, calculated as twist/LS, that takes into account actions that occur simultaneously during LV systole (i.e., longitudinal shortening and twist), was evaluated. Torsional and wringing parameters were calculated according to LVEF.

Introduction Aortic graft infections (AGI) can have catastrophic consequences with an operative mortality of nearly 50%. The majority of AGI are a result of bacterial exposure at the time of operation (surgical-site related), nearly three quarters a caused by the Staphylococcus organisms. Late onset infections are less common. The mechanism can be through hematogenous spread and bacterial invasion of the graft. Diagnosis is challenging, done by a combination of clinical, radiological and laboratory findings in which echocardiography plays an important role. Fundamental tenets of AGI management are removal of the infected device and adjunctive antimicrobial therapy. Case A 74-year-old man, who had undergone supracoronary ascending aortic replacement in 2015 for an aneurism, visited our hospital with fever of 39°, general malaise and abdominal pain for the last 3 days. He had been discharged one week ago after laparoscopic left colectomy due to descending colon neoplasia. Physical examination showed a systolic heart murmur loudest over the left-upper sternal border. Hematological findings included C-reactive protein (CRP) of 82 mg/l and white blood cell count of 16 700/μl. Blood culture was positive por Pseudomonas aeruginosa. Transthoracic echocardiography revealed a supravalvular pulmonary stenosis (figure 1, A) Transesophageal examination showed an extensive peritubular collection (figure 1, B) that extended into the main pulmonary artery, conditioning extrinsic compression and severe stenosis. No blood flow was observed inside the collection. A 6 mm long and filiform image was detected on the right coronary leaflet, causing a moderate aortic regurgitation. Chest CT revealed a low density area around the vascular graft (figure 1, C) and the positron emission tomography (PET)-CT (figure 1, D) showed increased glucidic metabolism in the aneurysmal sac, periaortic fat and the proximal and distal portion of the prosthesis. With the diagnosis of prosthetic vascular graft infection, the patient was referred to cardiac surgery. The surgical sample cultures (graft and mediastinal pus) were all positive for P. aeruginosa. The patient completed antibiotic therapy with ceftazidime and gentamicine. Discussion AGI is an extremely complex clinical challenge. Mortality is high, and diagnostic and treatment approaches are controversial. Cardiovascular imaging is one of the most important diagnostic tools in the diagnosis. An echocardiogram should be done in every patient to look for findings of endocarditis. CT is the most informative radiologic study and can be also very helpful in identifying characteristics and extension of AGI. A concurrent PET-CT study has significant potential in improving diagnosis of AGI and monitoring response to treatment.Nevertheless there is an unavoidable degree of subjective judgment in the interpretation of imaging findings making clinical suspicion and laboratory findings crucial in determining whether an AGI exists. Abstract P882 Figure.

No abstract