COVID-19 had led to severe clinical manifestations. In the current scenario, 98 794 942 people are infected, and it has responsible for 2 124 193 deaths around the world as reported by World Health Organization on 25 January 2021. Telemedicine has become a critical technology for providing medical care to patients by trying to reduce transmission of the virus among patients, families, and doctors. The economic consequences of coronavirus have affected the entire world and disrupted daily life in many countries. The development of telemedicine applications and eHealth services can significantly help to manage pandemic worldwide better. Consequently, the main objective of this paper is to present a systematic review of the implementation of telemedicine and e-health systems in the combat to COVID-19. The main contribution is to present a comprehensive description of the state of the art considering the domain areas, organizations, funding agencies, researcher units and authors involved. The results show that the United States and China have the most significant number of studies representing 42.11% and 31.58%, respectively. Furthermore, 35 different research units and 9 funding agencies are involved in the application of telemedicine systems to combat COVID-19.

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The actual challenge in health is to manage patients with chronic diseases from a holistic approach where technology around the patient and at the city enhances their wellness. This paper deepens in the relations between health, devices, and models of technological cities and how these can be modeled to provide a more cost efficient solution while less invasive and more natural to the end users. In light of this, usable and accessible software and a wide range of devices, ranging from PC, smartphone, tablet and SmartTV have been tested. This manuscript will give good comprehension on how technology and disease management care models interact with the patient.

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