Basal cell carcinoma (BCC) is the most frequent skin cancer. It never affects the mucosa. It is characterized by a local malignancy with an extremely rare risk of developing distant metastasis and the lowest mortality. However in the absence of diagnosis and early surgery, BCC can be locally invasive and result in severe tissue destruction. It can ulcerate and its growth can be extensive and destructive: terebrant tumors affecting the structures of the muscles and the bone. We here report the case of a 80-year old woman living in an isolated rural areas, presenting with ulcerated exudative and smelly burgeoning lesion in the pretragal and the parotid regions. Locoregional examination was unremarkable and histology showed infiltrative BCC. Staging evaluation objectified no bone invasion. The patient was referred to the Division of Plastic Surgery for carcinologic treatment.

Angiokeratomas are vascular dilations (telangiectasic papules) with keratotic surface caused by capillary dilation in the dermal papilla due to venous hyperpression, vascular malformation or a capillary fragility. They most commonly are benign and just unsightly and they may sometimes reveal a dreaded overload disease known as Fabry Disease. Here we report the case of a 56-year old patient, with no notable medical history, presenting with nontraumatic, nonpruritic, bleeding on contact, grouped cluster erythematous papules without extracutaneous manifestations on the left malar region, that had occurred 4 months before. Diascopy revealed partially emptied papules with keratotic surface. Kaposi syndrome, melanoma, carcinoma or angiokeratoma were suspected. Histological examination revealed angiokeratoma. Treatment based on electrocoagulation was proposed to the patient.

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Polymorphic lucite (PL) is a frequent photodermatosis, but its pathophysiologic mechanism is still poorly elucidated. We report the case of a 54-year old male teacher, with no previous medical-surgical history, presenting with recurrent papular and very pruritic rash lasting for 12 years. Clinical examination showed papular-vesicular excoriated lesions on the face, the neck and the scalp. Eczematiform lesions occurred on the back of the hands. The remainder of the integument as well as the mucous membranes were spared. The suspected diagnoses were lupus, drug-induced photosensitization or contact photosensitivity and polymorphic lucite (PL). During the interview, the patient reported that this eruption had recurred in the same period every year, namely at the beginning of spring and lasted until the end of summer. Photobiological evaluations were not performed. Antinuclear antibody test was negative, and histological examination was non-specific showing dermal dense lymphocytic infiltrate. The diagnosis of LP was suspected and the patient underwent synthetic antimalarial drug-based therapy associated with external photoprotection.

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