Objective: To determine frequency of microalbuminuria and relative determination of glycated hemoglobin (HBA1C) in Type II diabetes mellitus patients. Study Design: Descriptive Cross Sectional. Study Setting: Three Different Hospitals Based in Sindh Pakistan. Study Period: March-August 2021. Material & Methods: After selection through non-probability purposive sample technique, demographic details of all patients were noted in a written questionnaire. All the confirmed patients of type-II diabetes mellitus were then tested for microalbuminuria and glycated hemoglobin in parallel with the disease progression. All the collected information was analyzed in SPSS ver. 22. Results: Among 165 enrolled cases, 89 (54%) type II diabetic patients were normoalbuminuric, 53 (32 %) Microalbuminuria and 14 % macroalbuminuria. Males were at greater risk (65%) of developing type II diabetes mellitus in comparison to females (35%). In total 46 type II diabetes mellitus cases with microalbuminuria represent raised HBA1C levels AT95% CI. Conclusion: Prevalence of microalbuminuria among type II diabetic patients visiting the tertiary care hospital is 32.1%. Patients with higher HbA1c or poor glycemic control are present with microalbuminuria.