The revolution in semiconductor technology has lead to the development of efficient optical techniques for acquisition of biomedical signals which can be used effectively in diagnostics. The interaction of light with biological tissue is complex and includes the optical processes like scattering, absorption, reflection, transmission and fluorescence. The amount of light received by the photo-detector varies in accordance with the blood volume, blood vessel wall movement and the orientation of red blood cells (RBC). In the present work a real-time electro-optical based photoplethysmograpgh system is developed to monitor and record the variations in the volume of blood with each heart beat resulting in the form of a signal called photoplethysmogram (PPG). The developed sensor unit consists of a source of light and photo-detector both packed in the form of probe and fitted to patient's index finger. The PPG signal acquired comprise a pulsatile (AC) waveform attributed to cardiac synchronous changes in the blood volume with each heart beat and is superimposed on a slowly varying (DC) baseline with various lower frequency components attributed to respiration, sympathetic nervous system activity and thermoregulation. For remote monitoring of PPG signals, a system is designed and developed based on