People who have difficulty moving owing to problems in walking spend their lives assisted by wheelchairs. In the past, research has been conducted regarding the application of various technologies to electric wheelchairs for user convenience. In this study, we evaluated a method of applying an autonomous driving function and developed an autonomous driving function using ROS. An electric wheelchair with a control unit designed to enable autonomous driving was used to test the basic performance of autonomous driving. The effectiveness of the technology was confirmed by comparing the results of autonomous driving with those of manual driving on the same route. It is expected that the evaluation and improvement of the usability and ride quality as well as additional studies will help improve the mobility convenience of physically disabled persons.